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Aeroallergen Der p 2 promotes motility of human non-small cell lung cancer cells via toll-like receptor-mediated up-regulation of urokinase-type plasminogen activator and integrin/focal adhesion kinase signaling

House dust mite (HDM) allergens are one of the major causes leading to respiratory hypersensitiveness and airway remodeling. Here we hypothesized that a major HDM allergen Der p 2 could increase cell motility and invasiveness of non-small cell lung cancer (NSCLC) cells. Our results showed that low d...

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Detalles Bibliográficos
Autores principales: Lin, Chun-Hsiang, Lin, Hui-Han, Kuo, Cheng-Yi, Kao, Shao-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355267/
https://www.ncbi.nlm.nih.gov/pubmed/28076322
http://dx.doi.org/10.18632/oncotarget.14514