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Repression of Fyn-related kinase in breast cancer cells is associated with promoter site-specific CpG methylation
The triple-negative breast cancer subtype is highly aggressive and has no defined therapeutic target. Fyn-related kinase (FRK) is a non-receptor tyrosine kinase, reported to be downregulated in breast cancer and gliomas, where it is suggested to have tumor suppressor activity. We examined the expres...
Autores principales: | Bagu, Edward T., Miah, Sayem, Dai, Chenlu, Spriggs, Travis, Ogunbolude, Yetunde, Beaton, Erika, Sanders, Michelle, Goel, Raghuveera K., Bonham, Keith, Lukong, Kiven E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355277/ https://www.ncbi.nlm.nih.gov/pubmed/28077797 http://dx.doi.org/10.18632/oncotarget.14546 |
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