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Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia

Hypoxia-ischemia (HI) can result in permanent life-long injuries such as motor and cognitive deficits. In response to cellular stressors such as hypoxia, tumor suppressor protein p53 is activated, potently initiating apoptosis and promoting Bax-dependent mitochondrial outer membrane permeabilization...

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Detalles Bibliográficos
Autores principales:	Baburamani, Ana A, Sobotka, Kristina S, Vontell, Regina, Mallard, Carina, Supramaniam, Veena G, Thornton, Claire, Hagberg, Henrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355327/ https://www.ncbi.nlm.nih.gov/pubmed/28076846 http://dx.doi.org/10.18632/oncotarget.14518

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