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Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cells

The survival of patients diagnosed with glioblastoma (GBM), the most deadly form of brain cancer, is compromised by the proclivity for local invasion into the surrounding normal brain, which prevents complete surgical resection and contributes to therapeutic resistance. Tumor necrosis factor-like we...

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Detalles Bibliográficos
Autores principales: Roos, Alison, Dhruv, Harshil D., Mathews, Ian T., Inge, Landon J., Tuncali, Serdar, Hartman, Lauren K., Chow, Donald, Millard, Nghia, Yin, Holly H., Kloss, Jean, Loftus, Joseph C., Winkles, Jeffrey A., Berens, Michael E., Tran, Nhan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355340/
https://www.ncbi.nlm.nih.gov/pubmed/28103571
http://dx.doi.org/10.18632/oncotarget.14685