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Hypomethylation of HLA-DRB1 and its clinical significance in psoriasis

Increasing evidences indicate that the abnormal DNA methylation is involved in the pathogenesis of psoriasis. A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear that metylation status within HLA-DRB1 in psoriasis. Here, DNA and RNA were ob...

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Detalles Bibliográficos
Autores principales:	Zong, Wenkai, Ge, Yiping, Han, Yue, Yang, Xueyuan, Li, Qi, Chen, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Clinical Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355347/ https://www.ncbi.nlm.nih.gov/pubmed/27713139 http://dx.doi.org/10.18632/oncotarget.12468

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