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Transcriptomics Indicates Active and Passive Metronidazole Resistance Mechanisms in Three Seminal Giardia Lines
Giardia duodenalis is an intestinal parasite that causes 200–300 million episodes of diarrhoea annually. Metronidazole (Mtz) is a front-line anti-giardial, but treatment failure is common and clinical resistance has been demonstrated. Mtz is thought to be activated within the parasite by oxidoreduct...
Autores principales: | Ansell, Brendan R. E., Baker, Louise, Emery, Samantha J., McConville, Malcolm J., Svärd, Staffan G., Gasser, Robin B., Jex, Aaron R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355454/ https://www.ncbi.nlm.nih.gov/pubmed/28367140 http://dx.doi.org/10.3389/fmicb.2017.00398 |
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