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Rotation Mechanism of Molecular Motor V(1)-ATPase Studied by Multiscale Molecular Dynamics Simulation

Enterococcus hirae V(1)-ATPase is a molecular motor composed of the A(3)B(3) hexamer ring and the central stalk. In association with ATP hydrolysis, three catalytic AB pairs in the A(3)B(3) ring undergo conformational changes, which lead to a 120° rotation of the central stalk. To understand how the...

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Detalles Bibliográficos
Autores principales:	Isaka, Yuta, Ekimoto, Toru, Kokabu, Yuichi, Yamato, Ichiro, Murata, Takeshi, Ikeguchi, Mitsunori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2017
Materias:	Proteins
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355535/ https://www.ncbi.nlm.nih.gov/pubmed/28297650 http://dx.doi.org/10.1016/j.bpj.2017.01.029

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