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Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria
BACKGROUND: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. METHODS: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory b...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Occupational Safety and Health Research Institute
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355539/ https://www.ncbi.nlm.nih.gov/pubmed/28344841 http://dx.doi.org/10.1016/j.shaw.2016.08.002 |
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author | Odetokun, Ismail Ayoade Jagun-Jubril, Afusat Toyin Onoja, Bernard A. Wungak, Yiltawe Simwal Raufu, Ibrahim Adisa Chen, Jessica Corron |
author_facet | Odetokun, Ismail Ayoade Jagun-Jubril, Afusat Toyin Onoja, Bernard A. Wungak, Yiltawe Simwal Raufu, Ibrahim Adisa Chen, Jessica Corron |
author_sort | Odetokun, Ismail Ayoade |
collection | PubMed |
description | BACKGROUND: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. METHODS: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression. RESULTS: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1–3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE. CONCLUSIONS: Current knowledge of laboratory biosafety is limited except among a few researchers. |
format | Online Article Text |
id | pubmed-5355539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Occupational Safety and Health Research Institute |
record_format | MEDLINE/PubMed |
spelling | pubmed-53555392017-03-24 Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria Odetokun, Ismail Ayoade Jagun-Jubril, Afusat Toyin Onoja, Bernard A. Wungak, Yiltawe Simwal Raufu, Ibrahim Adisa Chen, Jessica Corron Saf Health Work Original Article BACKGROUND: This study determined current status of laboratory biosafety in Nigerian veterinary research facilities. METHODS: A questionnaire was developed to obtain information from researchers across Nigeria from July 2014 to July 2015. Information regarding demographics, knowledge of laboratory biosafety, availability and proper use of personal protective equipment (PPE), any priority pathogens researched, attitude on and use of standard laboratory practices, and biosafety awareness was obtained using a numeric scoring system. Data were analyzed with descriptive statistics, and univariate and multivariate logistic regression. RESULTS: A total of 74 participants from 19 facilities completed the questionnaire. General knowledge scores ranged from 3 to 28 (out of 28 possible points), with 94.6% of respondents receiving low scores (scores < mean + 1 standard deviation). Very few (17.6%) reported availability or use PPE. Many participants (63.5%) reported no access to biosafety level (BSL)-1–3 facilities. None reported availability of a BSL-4 facility. Knowledge scores pertaining to biosafety management practices ranged from 0 to 14 (out of 14 possible points) with 47.3% of respondents receiving good scores (scores > mean + 1 standard deviation). Only 16.2% of respondents (from four facilities) reported having biosafety officers. Rabies virus was the most researched pathogen (31.1% of respondents). The majority (71.6%) were unaware of laws guiding biosafety. Researchers [odds ratio (OR) = 18.0; 95% confidence interval (CI): 1.63, 198.5; p = 0.023], especially in BSL-2 (OR = 258.5; 95% CI: 12.71, 5256; p < 0.001) facility of research institute (OR = 25.0; 95% CI: 5.18, 120.6; p < 0.001), are more likely to have adequate access to and properly utilize biosafety devices and PPE. CONCLUSIONS: Current knowledge of laboratory biosafety is limited except among a few researchers. Occupational Safety and Health Research Institute 2017-03 2016-08-26 /pmc/articles/PMC5355539/ /pubmed/28344841 http://dx.doi.org/10.1016/j.shaw.2016.08.002 Text en © 2016, Occupational Safety and Health Research Institute. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Odetokun, Ismail Ayoade Jagun-Jubril, Afusat Toyin Onoja, Bernard A. Wungak, Yiltawe Simwal Raufu, Ibrahim Adisa Chen, Jessica Corron Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title_full | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title_fullStr | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title_full_unstemmed | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title_short | Status of Laboratory Biosafety and Biosecurity in Veterinary Research Facilities in Nigeria |
title_sort | status of laboratory biosafety and biosecurity in veterinary research facilities in nigeria |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355539/ https://www.ncbi.nlm.nih.gov/pubmed/28344841 http://dx.doi.org/10.1016/j.shaw.2016.08.002 |
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