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Prolonged exposure of colon cancer cells to 5-fluorouracil nanoparticles improves its anticancer activity
In this study, we aimed to improve the anticancer effect of 5-FU on human colon cancer cell lines by incorporating in poly(d,l lactic-co-glycolic acid) (PLGA) nanoparticles (NPs). The 5-FU-PLGA NPs were prepared by nanoprecipitation technique. Prepared NPs were moderately dispersed with an average d...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355554/ https://www.ncbi.nlm.nih.gov/pubmed/28344470 http://dx.doi.org/10.1016/j.jsps.2016.05.010 |