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Prolonged exposure of colon cancer cells to 5-fluorouracil nanoparticles improves its anticancer activity

In this study, we aimed to improve the anticancer effect of 5-FU on human colon cancer cell lines by incorporating in poly(d,l lactic-co-glycolic acid) (PLGA) nanoparticles (NPs). The 5-FU-PLGA NPs were prepared by nanoprecipitation technique. Prepared NPs were moderately dispersed with an average d...

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Detalles Bibliográficos
Autores principales:	Tawfik, Essam, Ahamed, Maqusood, Almalik, Abdulaziz, Alfaqeeh, Mohammad, Alshamsan, Aws
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355554/ https://www.ncbi.nlm.nih.gov/pubmed/28344470 http://dx.doi.org/10.1016/j.jsps.2016.05.010

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