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Subependymal Zone-Derived Oligodendroblasts Respond to Focal Demyelination but Fail to Generate Myelin in Young and Aged Mice

Two populations of oligodendrogenic progenitors co-exist within the corpus callosum (CC) of the adult mouse. Local, parenchymal oligodendrocyte progenitor cells (pOPCs) and progenitors generated in the subependymal zone (SEZ) cytogenic niche. pOPCs are committed perinatally and retain their numbers...

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Detalles Bibliográficos
Autores principales: Kazanis, Ilias, Evans, Kimberley A., Andreopoulou, Evangelia, Dimitriou, Christina, Koutsakis, Christos, Karadottir, Ragnhildur Thora, Franklin, Robin J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355571/
https://www.ncbi.nlm.nih.gov/pubmed/28196689
http://dx.doi.org/10.1016/j.stemcr.2017.01.007

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