Neutralization of Diverse Human Cytomegalovirus Strains Conferred by Antibodies Targeting Viral gH/gL/pUL128-131 Pentameric Complex

Human cytomegalovirus (HCMV) is the leading cause of congenital viral infection, and developing a prophylactic vaccine is of high priority to public health. We recently reported a replication-defective human cytomegalovirus with restored pentameric complex glycoprotein H (gH)/gL/pUL128-131 for preve...

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Detalles Bibliográficos
Autores principales: Ha, Sha, Li, Fengsheng, Troutman, Matthew C., Freed, Daniel C., Tang, Aimin, Loughney, John W., Wang, Dai, Wang, I-Ming, Vlasak, Josef, Nickle, David C., Rustandi, Richard R., Hamm, Melissa, DePhillips, Pete A., Zhang, Ningyan, McLellan, Jason S., Zhu, Hua, Adler, Stuart P., McVoy, Michael A., An, Zhiqiang, Fu, Tong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355600/
https://www.ncbi.nlm.nih.gov/pubmed/28077654
http://dx.doi.org/10.1128/JVI.02033-16

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