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Role of the PB2 627 Domain in Influenza A Virus Polymerase Function

The RNA genome of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB2. High-resolution structural data revealed that the polymerase assembles into a central polymerase core and several auxiliary highly flexible, protr...

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Detalles Bibliográficos
Autores principales: Nilsson, Benjamin E., te Velthuis, Aartjan J. W., Fodor, Ervin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355620/
https://www.ncbi.nlm.nih.gov/pubmed/28122973
http://dx.doi.org/10.1128/JVI.02467-16