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Spirulina lipopolysaccharides inhibit tumor growth in a Toll-like receptor 4-dependent manner by altering the cytokine milieu from interleukin-17/interleukin-23 to interferon-γ
Th17 cells and the cytokine they produce, interleukin (IL)-17, play an important role in tumor progression in humans and in mice. IL-6 and IL-23 are critical cytokines for the differentiation and propagation of Th17 cells, respectively. Bacterial lipopolysaccharides (LPS) are known to stimulate immu...
Autores principales: | Okuyama, Hiromi, Tominaga, Akira, Fukuoka, Satoshi, Taguchi, Takahiro, Kusumoto, Yutaka, Ono, Shiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355664/ https://www.ncbi.nlm.nih.gov/pubmed/28075473 http://dx.doi.org/10.3892/or.2017.5346 |
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