In Vitro Modeling of Blood-Brain Barrier with Human iPSC-Derived Endothelial Cells, Pericytes, Neurons, and Astrocytes via Notch Signaling

The blood-brain barrier (BBB) is composed of four cell populations, brain endothelial cells (BECs), pericytes, neurons, and astrocytes. Its role is to precisely regulate the microenvironment of the brain through selective substance crossing. Here we generated an in vitro model of the BBB by differen...

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Detalles Bibliográficos
Autores principales: Yamamizu, Kohei, Iwasaki, Mio, Takakubo, Hitomi, Sakamoto, Takumi, Ikuno, Takeshi, Miyoshi, Mami, Kondo, Takayuki, Nakao, Yoichi, Nakagawa, Masato, Inoue, Haruhisa, Yamashita, Jun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355679/
https://www.ncbi.nlm.nih.gov/pubmed/28238797
http://dx.doi.org/10.1016/j.stemcr.2017.01.023

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