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Oxymatrine inhibits the migration of human colorectal carcinoma RKO cells via inhibition of PAI-1 and the TGF-β1/Smad signaling pathway

Transforming growth factor-β1 (TGF-β1) signaling has been shown to play a critical role in the development of epithelial-mesenchymal transition (EMT). PAI-1 is one of the most important target genes in the TGF-β/Smad signaling pathway, which can hinder the degradation of ECM composition and may prom...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaoyu, Liu, Chun, Wang, Jiaqi, Fan, Yue, Wang, Zhenghua, Wang, Yuanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355745/ https://www.ncbi.nlm.nih.gov/pubmed/27959430 http://dx.doi.org/10.3892/or.2016.5292

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