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Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera

Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-princ...

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Autores principales: Israel, Yonatan, Tenne, Ron, Oron, Dan, Silberberg, Yaron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355801/
https://www.ncbi.nlm.nih.gov/pubmed/28287167
http://dx.doi.org/10.1038/ncomms14786
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author Israel, Yonatan
Tenne, Ron
Oron, Dan
Silberberg, Yaron
author_facet Israel, Yonatan
Tenne, Ron
Oron, Dan
Silberberg, Yaron
author_sort Israel, Yonatan
collection PubMed
description Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-principle demonstrations. This is primarily due to a combination of low values of fill factors, quantum efficiencies, frame rates and signal-to-noise characteristic of most available single-photon sensitive imaging detectors. Here we describe an imaging device based on a fibre bundle coupled to single-photon avalanche detectors that combines a large fill factor, a high quantum efficiency, a low noise and scalable architecture. Our device enables localization-based super-resolution microscopy in a non-sparse non-stationary scene, utilizing information on the number of active emitters, as gathered from non-classical photon statistics.
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spelling pubmed-53558012017-04-17 Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera Israel, Yonatan Tenne, Ron Oron, Dan Silberberg, Yaron Nat Commun Article Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-principle demonstrations. This is primarily due to a combination of low values of fill factors, quantum efficiencies, frame rates and signal-to-noise characteristic of most available single-photon sensitive imaging detectors. Here we describe an imaging device based on a fibre bundle coupled to single-photon avalanche detectors that combines a large fill factor, a high quantum efficiency, a low noise and scalable architecture. Our device enables localization-based super-resolution microscopy in a non-sparse non-stationary scene, utilizing information on the number of active emitters, as gathered from non-classical photon statistics. Nature Publishing Group 2017-03-13 /pmc/articles/PMC5355801/ /pubmed/28287167 http://dx.doi.org/10.1038/ncomms14786 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Israel, Yonatan
Tenne, Ron
Oron, Dan
Silberberg, Yaron
Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title_full Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title_fullStr Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title_full_unstemmed Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title_short Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
title_sort quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355801/
https://www.ncbi.nlm.nih.gov/pubmed/28287167
http://dx.doi.org/10.1038/ncomms14786
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