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Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera
Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-princ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355801/ https://www.ncbi.nlm.nih.gov/pubmed/28287167 http://dx.doi.org/10.1038/ncomms14786 |
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author | Israel, Yonatan Tenne, Ron Oron, Dan Silberberg, Yaron |
author_facet | Israel, Yonatan Tenne, Ron Oron, Dan Silberberg, Yaron |
author_sort | Israel, Yonatan |
collection | PubMed |
description | Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-principle demonstrations. This is primarily due to a combination of low values of fill factors, quantum efficiencies, frame rates and signal-to-noise characteristic of most available single-photon sensitive imaging detectors. Here we describe an imaging device based on a fibre bundle coupled to single-photon avalanche detectors that combines a large fill factor, a high quantum efficiency, a low noise and scalable architecture. Our device enables localization-based super-resolution microscopy in a non-sparse non-stationary scene, utilizing information on the number of active emitters, as gathered from non-classical photon statistics. |
format | Online Article Text |
id | pubmed-5355801 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-53558012017-04-17 Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera Israel, Yonatan Tenne, Ron Oron, Dan Silberberg, Yaron Nat Commun Article Despite advances in low-light-level detection, single-photon methods such as photon correlation have rarely been used in the context of imaging. The few demonstrations, for example of subdiffraction-limited imaging utilizing quantum statistics of photons, have remained in the realm of proof-of-principle demonstrations. This is primarily due to a combination of low values of fill factors, quantum efficiencies, frame rates and signal-to-noise characteristic of most available single-photon sensitive imaging detectors. Here we describe an imaging device based on a fibre bundle coupled to single-photon avalanche detectors that combines a large fill factor, a high quantum efficiency, a low noise and scalable architecture. Our device enables localization-based super-resolution microscopy in a non-sparse non-stationary scene, utilizing information on the number of active emitters, as gathered from non-classical photon statistics. Nature Publishing Group 2017-03-13 /pmc/articles/PMC5355801/ /pubmed/28287167 http://dx.doi.org/10.1038/ncomms14786 Text en Copyright © 2017, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Israel, Yonatan Tenne, Ron Oron, Dan Silberberg, Yaron Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title | Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title_full | Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title_fullStr | Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title_full_unstemmed | Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title_short | Quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
title_sort | quantum correlation enhanced super-resolution localization microscopy enabled by a fibre bundle camera |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355801/ https://www.ncbi.nlm.nih.gov/pubmed/28287167 http://dx.doi.org/10.1038/ncomms14786 |
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