Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

Human induced pluripotent stem cells (iPSCs) are promising in regenerative medicine. However, the risks of teratoma formation and the overgrowth of the transplanted cells continue to be major hurdles that must be overcome. Here, we examined the efficacy of the inducible caspase-9 (iCaspase9) gene as...

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Detalles Bibliográficos
Autores principales: Itakura, Go, Kawabata, Soya, Ando, Miki, Nishiyama, Yuichiro, Sugai, Keiko, Ozaki, Masahiro, Iida, Tsuyoshi, Ookubo, Toshiki, Kojima, Kota, Kashiwagi, Rei, Yasutake, Kaori, Nakauchi, Hiromitsu, Miyoshi, Hiroyuki, Nagoshi, Narihito, Kohyama, Jun, Iwanami, Akio, Matsumoto, Morio, Nakamura, Masaya, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355810/
https://www.ncbi.nlm.nih.gov/pubmed/28262544
http://dx.doi.org/10.1016/j.stemcr.2017.02.003

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