E3 ligase FBXW7 is critical for RIG-I stabilization during antiviral responses

Viruses can escape from host recognition by degradation of RIG-I or interference with the RIG-I signalling to establish persistent infections. However, the mechanisms by which host cells stabilize RIG-I protein for avoiding its degradation are largely unknown. We report here that, upon virus infecti...

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Detalles Bibliográficos
Autores principales: Song, Yinjing, Lai, Lihua, Chong, Zhenlu, He, Jia, Zhang, Yuanyuan, Xue, Yue, Xie, Yiwei, Chen, Songchang, Dong, Ping, Chen, Luoquan, Chen, Zhimin, Dai, Feng, Wan, Xiaopeng, Xiao, Peng, Cao, Xuetao, Liu, Yang, Wang, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355826/
https://www.ncbi.nlm.nih.gov/pubmed/28287082
http://dx.doi.org/10.1038/ncomms14654

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