A novel route for preparing 5′ cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistry

The significant biological role of the mRNA 5′ cap in translation initiation makes it an interesting subject for chemical modifications aimed at producing useful tools for the selective modulation of intercellular processes and development of novel therapeutic interventions. However, traditional app...

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Detalles Bibliográficos
Autores principales: Walczak, Sylwia, Nowicka, Anna, Kubacka, Dorota, Fac, Kaja, Wanat, Przemyslaw, Mroczek, Seweryn, Kowalska, Joanna, Jemielity, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355871/
https://www.ncbi.nlm.nih.gov/pubmed/28451173
http://dx.doi.org/10.1039/c6sc02437h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355871/
https://www.ncbi.nlm.nih.gov/pubmed/28451173
http://dx.doi.org/10.1039/c6sc02437h

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