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Investigation of the action of poly(ADP-ribose)-synthesising enzymes on NAD(+) analogues

ADP-ribosyl transferases with diphtheria toxin homology (ARTDs) catalyse the covalent addition of ADP-ribose onto different acceptors forming mono- or poly(ADP-ribos)ylated proteins. Out of the 18 members identified, only four are known to synthesise the complex poly(ADP-ribose) biopolymer. The inve...

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Detalles Bibliográficos
Autores principales: Wallrodt, Sarah, Simpson, Edward L, Marx, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355910/
https://www.ncbi.nlm.nih.gov/pubmed/28382184
http://dx.doi.org/10.3762/bjoc.13.49

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