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ORAI2 modulates store-operated calcium entry and T cell-mediated immunity

Store-operated Ca(2+) entry (SOCE) through Ca(2+) release-activated Ca(2+) (CRAC) channels is critical for lymphocyte function and immune responses. CRAC channels are hexamers of ORAI proteins that form the channel pore, but the contributions of individual ORAI homologues to CRAC channel function ar...

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Detalles Bibliográficos
Autores principales:	Vaeth, Martin, Yang, Jun, Yamashita, Megumi, Zee, Isabelle, Eckstein, Miriam, Knosp, Camille, Kaufmann, Ulrike, Karoly Jani, Peter, Lacruz, Rodrigo S., Flockerzi, Veit, Kacskovics, Imre, Prakriya, Murali, Feske, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355949/ https://www.ncbi.nlm.nih.gov/pubmed/28294127 http://dx.doi.org/10.1038/ncomms14714

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