An excessive increase in glutamate contributes to glucose-toxicity in β-cells via activation of pancreatic NMDA receptors in rodent diabetes

In the nervous system, excessive activation of NMDA receptors causes neuronal injury. Although activation of NMDARs has been proposed to contribute to the progress of diabetes, little is known about the effect of excessive long-term activation of NMDARs on β-cells, especially under the challenge of...

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Detalles Bibliográficos
Autores principales: Huang, Xiao-Ting, Li, Chen, Peng, Xiang-Ping, Guo, Jia, Yue, Shao-Jie, Liu, Wei, Zhao, Fei-Yan, Han, Jian-Zhong, Huang, Yan-Hong, Yang-Li, Y -L, Cheng, Qing-Mei, Zhou, Zhi-Guang, Chen, Chen, Feng, Dan-Dan, Luo, Zi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356012/
https://www.ncbi.nlm.nih.gov/pubmed/28303894
http://dx.doi.org/10.1038/srep44120

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