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Suppression of Sin3A activity promotes differentiation of pluripotent cells into functional neurons

Sin3 is a transcriptional corepressor for REST silencing machinery that represses multiple neuronal genes in non-neuronal cells. However, functions of Sin3 (Sin3A and Sin3B) in suppression of neuronal phenotypes are not well characterized. Herein we show that Sin3A knockdown impedes the repressive a...

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Detalles Bibliográficos
Autores principales:	Halder, Debasish, Lee, Chang-Hee, Hyun, Ji Young, Chang, Gyeong-Eon, Cheong, Eunji, Shin, Injae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356016/ https://www.ncbi.nlm.nih.gov/pubmed/28303954 http://dx.doi.org/10.1038/srep44818

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