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The role of imaging in the diagnosis of primary prostate cancer
Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state followin...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356180/ https://www.ncbi.nlm.nih.gov/pubmed/28344811 http://dx.doi.org/10.1177/2051415816656120 |
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author | Harvey, Hugh deSouza, Nandita M |
author_facet | Harvey, Hugh deSouza, Nandita M |
author_sort | Harvey, Hugh |
collection | PubMed |
description | Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state following injection of weakly paramagnetic agents such as gadolinium. Together these parameters are referred to as multiparametric (mp)MRI and are used for detecting and guiding biopsy and staging prostate cancer. Although sensitivity of mpMRI is <75% for disease detection, specificity is >90% and a standardised reporting system together with MR-guided targeted biopsy is the optimal diagnostic pathway. Shear wave ultrasound elastography is a new technique which also holds promise for future studies. This article describes the developments in imaging the primary site of prostate cancer and reviews their current and future utility for screening, diagnosis and T-staging the disease. |
format | Online Article Text |
id | pubmed-5356180 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-53561802017-03-23 The role of imaging in the diagnosis of primary prostate cancer Harvey, Hugh deSouza, Nandita M J Clin Urol Changing Face of Prostate Cancer Diagnosis and Management Ultrasound and magnetic resonance imaging (MRI) are key imaging modalities in prostate cancer diagnosis. MRI offers a range of intrinsic contrast mechanisms (T2, diffusion-weighted imaging (DWI), MR spectroscopy (MRS)) and extrinsic contrast-generating options based on tumour vascular state following injection of weakly paramagnetic agents such as gadolinium. Together these parameters are referred to as multiparametric (mp)MRI and are used for detecting and guiding biopsy and staging prostate cancer. Although sensitivity of mpMRI is <75% for disease detection, specificity is >90% and a standardised reporting system together with MR-guided targeted biopsy is the optimal diagnostic pathway. Shear wave ultrasound elastography is a new technique which also holds promise for future studies. This article describes the developments in imaging the primary site of prostate cancer and reviews their current and future utility for screening, diagnosis and T-staging the disease. SAGE Publications 2016-12-01 2016-12 /pmc/articles/PMC5356180/ /pubmed/28344811 http://dx.doi.org/10.1177/2051415816656120 Text en © British Association of Urological Surgeons 2017 http://creativecommons.org/licenses/by-nc/3.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Changing Face of Prostate Cancer Diagnosis and Management Harvey, Hugh deSouza, Nandita M The role of imaging in the diagnosis of primary prostate cancer |
title | The role of imaging in the diagnosis of primary prostate cancer |
title_full | The role of imaging in the diagnosis of primary prostate cancer |
title_fullStr | The role of imaging in the diagnosis of primary prostate cancer |
title_full_unstemmed | The role of imaging in the diagnosis of primary prostate cancer |
title_short | The role of imaging in the diagnosis of primary prostate cancer |
title_sort | role of imaging in the diagnosis of primary prostate cancer |
topic | Changing Face of Prostate Cancer Diagnosis and Management |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356180/ https://www.ncbi.nlm.nih.gov/pubmed/28344811 http://dx.doi.org/10.1177/2051415816656120 |
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