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Current concepts of active vasodilation in human skin
In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in evaporative cooling of the skin. Cutaneous vasodilation...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356216/ https://www.ncbi.nlm.nih.gov/pubmed/28349094 http://dx.doi.org/10.1080/23328940.2016.1200203 |
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author | Wong, Brett J. Hollowed, Casey G. |
author_facet | Wong, Brett J. Hollowed, Casey G. |
author_sort | Wong, Brett J. |
collection | PubMed |
description | In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in evaporative cooling of the skin. Cutaneous vasodilation and sudomotor activity are controlled by a sympathetic cholinergic active vasodilator system that is hypothesized to operate through a co-transmission mechanism. To date, mechanisms of cutaneous active vasodilation remain equivocal despite many years of research by several productive laboratory groups. The purpose of this review is to highlight recent advancements in the field of cutaneous active vasodilation framed in the context of some of the historical findings that laid the groundwork for our current understanding of cutaneous active vasodilation. |
format | Online Article Text |
id | pubmed-5356216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-53562162017-03-27 Current concepts of active vasodilation in human skin Wong, Brett J. Hollowed, Casey G. Temperature (Austin) Comprehensive Review In humans, an increase in internal core temperature elicits large increases in skin blood flow and sweating. The increase in skin blood flow serves to transfer heat via convection from the body core to the skin surface while sweating results in evaporative cooling of the skin. Cutaneous vasodilation and sudomotor activity are controlled by a sympathetic cholinergic active vasodilator system that is hypothesized to operate through a co-transmission mechanism. To date, mechanisms of cutaneous active vasodilation remain equivocal despite many years of research by several productive laboratory groups. The purpose of this review is to highlight recent advancements in the field of cutaneous active vasodilation framed in the context of some of the historical findings that laid the groundwork for our current understanding of cutaneous active vasodilation. Taylor & Francis 2016-06-21 /pmc/articles/PMC5356216/ /pubmed/28349094 http://dx.doi.org/10.1080/23328940.2016.1200203 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted. |
spellingShingle | Comprehensive Review Wong, Brett J. Hollowed, Casey G. Current concepts of active vasodilation in human skin |
title | Current concepts of active vasodilation in human skin |
title_full | Current concepts of active vasodilation in human skin |
title_fullStr | Current concepts of active vasodilation in human skin |
title_full_unstemmed | Current concepts of active vasodilation in human skin |
title_short | Current concepts of active vasodilation in human skin |
title_sort | current concepts of active vasodilation in human skin |
topic | Comprehensive Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356216/ https://www.ncbi.nlm.nih.gov/pubmed/28349094 http://dx.doi.org/10.1080/23328940.2016.1200203 |
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