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MicroRNA-142 regulates inflammation and T cell differentiation in an animal model of multiple sclerosis

BACKGROUND: MicroRNAs have emerged as an important class of modulators of gene expression. These molecules influence protein synthesis through translational repression or degradation of mRNA transcripts. Herein, we investigated the potential role of miR-142a isoforms, miR-142a-3p and miR-142a-5p, in...

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Detalles Bibliográficos
Autores principales: Talebi, Farideh, Ghorbani, Samira, Chan, Wing Fuk, Boghozian, Roobina, Masoumi, Farimah, Ghasemi, Sedigheh, Vojgani, Mohammed, Power, Christopher, Noorbakhsh, Farshid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356264/
https://www.ncbi.nlm.nih.gov/pubmed/28302134
http://dx.doi.org/10.1186/s12974-017-0832-7