Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma

Fibrolamellar carcinoma (FLC) is a unique liver cancer primarily affecting young adults and characterized by a fusion event between DNAJB1 and PRKACA. By analyzing RNA-sequencing data from The Cancer Genome Atlas (TCGA) for >9,100 tumors across ~30 cancer types, we show that the DNAJB1-PRKACA fus...

Descripción completa

Detalles Bibliográficos
Autores principales: Dinh, Timothy A., Vitucci, Eva C. M., Wauthier, Eliane, Graham, Rondell P., Pitman, Wendy A., Oikawa, Tsunekazu, Chen, Mengjie, Silva, Grace O., Greene, Kevin G., Torbenson, Michael S., Reid, Lola M., Sethupathy, Praveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356346/
https://www.ncbi.nlm.nih.gov/pubmed/28304380
http://dx.doi.org/10.1038/srep44653

Ejemplares similares

Ejemplares similares