Cargando…
Ninein is essential for apico-basal microtubule formation and CLIP-170 facilitates its redeployment to non-centrosomal microtubule organizing centres
Differentiation of columnar epithelial cells involves a dramatic reorganization of the microtubules (MTs) and centrosomal components into an apico-basal array no longer anchored at the centrosome. Instead, the minus-ends of the MTs become anchored at apical non-centrosomal microtubule organizing cen...
Autores principales: | Goldspink, Deborah A., Rookyard, Chris, Tyrrell, Benjamin J., Gadsby, Jonathan, Perkins, James, Lund, Elizabeth K., Galjart, Niels, Thomas, Paul, Wileman, Tom, Mogensen, Mette M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356440/ https://www.ncbi.nlm.nih.gov/pubmed/28179500 http://dx.doi.org/10.1098/rsob.160274 |
Ejemplares similares
-
Ninein is essential for the maintenance of the cortical progenitor character by anchoring the centrosome to microtubules
por: Shinohara, Hiroshi, et al.
Publicado: (2013) -
Immuno-fluorescent Labeling of Microtubules and Centrosomal Proteins in Ex Vivo Intestinal Tissue and 3D In Vitro Intestinal Organoids
por: Goldspink, Deborah A., et al.
Publicado: (2017) -
Dynamic Localization of CLIP-170 to Microtubule Plus Ends Is Coupled to Microtubule Assembly
por: Diamantopoulos, Georgios S., et al.
Publicado: (1999) -
Conformational changes in CLIP-170 regulate its binding to microtubules and dynactin localization
por: Lansbergen, Gideon, et al.
Publicado: (2004) -
Dynamic behavior of GFP–CLIP-170 reveals fast protein turnover on microtubule plus ends
por: Dragestein, Katharina A., et al.
Publicado: (2008)