A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism

Unlike most bacteria, mycobacteria rely on the multi-domain enzyme eukaryote-like fatty acid synthase I (FAS I) to make fatty acids de novo. These metabolites are precursors of the biosynthesis of most of the lipids present both in the complex mycobacteria cell wall and in the storage lipids inside...

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Detalles Bibliográficos
Autores principales: Cabruja, Matías, Mondino, Sonia, Tsai, Yi Ting, Lara, Julia, Gramajo, Hugo, Gago, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356441/
https://www.ncbi.nlm.nih.gov/pubmed/28228470
http://dx.doi.org/10.1098/rsob.160277

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