Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells

The human cytomegalovirus (HCMV) encoded chemokine receptor US28 promotes tumorigenesis through activation of various proliferative and angiogenic signaling pathways. Upon infection, US28 displays constitutive activity and signals in a G protein-dependent manner, hijacking the host's cellular m...

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Detalles Bibliográficos
Autores principales: de Wit, Raymond H., Mujić-Delić, Azra, van Senten, Jeffrey R., Fraile-Ramos, Alberto, Siderius, Marco, Smit, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356532/
https://www.ncbi.nlm.nih.gov/pubmed/27602585
http://dx.doi.org/10.18632/oncotarget.11817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356532/
https://www.ncbi.nlm.nih.gov/pubmed/27602585
http://dx.doi.org/10.18632/oncotarget.11817

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