The antiangiogenic effects of polyisoprenylated cysteinyl amide inhibitors in HUVEC, chick embryo and zebrafish is dependent on the polyisoprenyl moiety

Angiogenesis is essential for solid tumor growth, therapeutic resistance and metastasis, the latest accounting for 90% of cancer deaths. Although angiogenesis is essential for the malignant transformations in solid tumors and therefore is an attractive target, few drugs are available that block tumo...

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Detalles Bibliográficos
Autores principales: Nkembo, Augustine T., Ntantie, Elizabeth, Salako, Olufisayo O., Amissah, Felix, Poku, Rosemary A., Latinwo, Lekan M., Lamango, Nazarius S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356549/
https://www.ncbi.nlm.nih.gov/pubmed/27626690
http://dx.doi.org/10.18632/oncotarget.11908

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