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CD74 interacts with CD44 and enhances tumorigenesis and metastasis via RHOA-mediated cofilin phosphorylation in human breast cancer cells

CD74, also known as Ii, was initially considered to participate primarily in antigen presentation. Subsequent studies have shown that CD74 is highly expressed in various types of tumor cells and has multiple roles in a variety of biological processes. CD74 is thought to promote breast cancer metasta...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyong, Chu, Shuzhou, Yao, Shun, Li, Yu, Fan, Songqing, Sun, Xiaoyang, Su, Ling, Liu, Xiangguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356556/
https://www.ncbi.nlm.nih.gov/pubmed/27626171
http://dx.doi.org/10.18632/oncotarget.11945