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Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model
Inheritance of a gene mutation leads to the initiation of 5 to 10% of most cancers, including colon cancer cases. We developed a chemoprevention strategy using a novel combination of the non-steroidal anti-inflammatory (NSAID) sulindac plus the anthelminthic benzimidazole, mebendazole. This oral dru...
Autores principales: | Williamson, Tara, Bai, Ren-Yuan, Staedtke, Verena, Huso, David, Riggins, Gregory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356574/ https://www.ncbi.nlm.nih.gov/pubmed/27612418 http://dx.doi.org/10.18632/oncotarget.11851 |
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