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Pathological complete response after cisplatin neoadjuvant therapy is associated with the downregulation of DNA repair genes in BRCA1-associated triple-negative breast cancers
Pathologic complete response (pCR) after neoadjuvant chemotherapy is considered a suitable surrogate marker of treatment efficacy in patients with triple-negative breast cancers (TNBCs). However, the molecular mechanisms underlying pCR as a result of such treatment remain obscure. Using real-time PC...
Autores principales: | Domagala, Pawel, Hybiak, Jolanta, Rys, Janusz, Byrski, Tomasz, Cybulski, Cezary, Lubinski, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356581/ https://www.ncbi.nlm.nih.gov/pubmed/27626685 http://dx.doi.org/10.18632/oncotarget.11900 |
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