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Environmental Xenoestrogens Super-Activate a Variant Murine ER Beta in Cholangiocytes

High systemic levels of oestrogens are cholestatic and primary biliary cholangitis (PBC)—which is characterized by hepatic ductular inflammation—is thought to be triggered by exposure to xenobiotics such as those around landfill sites. Xenoestrogens may be a component of this chemical trigger. We th...

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Detalles Bibliográficos
Autores principales:	Meyer, Stephanie K., Probert, Philip M. E., Lakey, Anne K., Leitch, Alastair C., Blake, Lynsay I., Jowsey, Paul A., Cooke, Martin P., Blain, Peter G., Wright, Matthew C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Environmental Estrogens and Receptor Activation In Bile Duct Epithelium
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356623/ https://www.ncbi.nlm.nih.gov/pubmed/28013213 http://dx.doi.org/10.1093/toxsci/kfw234

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