Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis

Accumulation of hydrophobic bile acids in the liver contributes to cholestatic liver injury. Inflammation induced by excessive bile acids is believed to play a crucial role, however, the mechanisms of bile acids triggered inflammatory response remain unclear. Recent studies have highlighted the effe...

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Detalles Bibliográficos
Autores principales: Gong, Zizhen, Zhou, Jiefei, Zhao, Shengnan, Tian, Chunyan, Wang, Panliang, Xu, Congfeng, Chen, Yingwei, Cai, Wei, Wu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356637/
https://www.ncbi.nlm.nih.gov/pubmed/27924062
http://dx.doi.org/10.18632/oncotarget.13796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356637/
https://www.ncbi.nlm.nih.gov/pubmed/27924062
http://dx.doi.org/10.18632/oncotarget.13796

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