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Aberrant localization of apoptosis protease activating factor-1 in lipid raft sub-domains of diffuse large B cell lymphomas
Resistance to chemotherapy remains a challenge in the clinical management of diffuse B cell lymphomas despite aggressive chemotherapy such as CHOP and monoclonal CD20. Here we provide evidence that the apoptosome adaptor protein, Apaf-1, is mislocalized in primary cells derived from patients with di...
Autores principales: | Hirpara, Jayshree L., Loh, Thomas, Ng, Siok Bian, Chng, Wee Joo, Pervaiz, Shazib |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356638/ https://www.ncbi.nlm.nih.gov/pubmed/27863378 http://dx.doi.org/10.18632/oncotarget.13336 |
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