Application of pharmacologically induced transcriptomic profiles to interrogate PI3K-Akt-mTOR pathway activity associated with cancer patient prognosis

The PI3K-Akt-mTOR signaling pathway has been identified as a key driver of carcinogenesis in several cancer types. As such, a major area of focus in cancer biology is the development of genomic biomarkers that can measure the activity level of the PI3K-Akt-mTOR pathway. In this study, we systematica...

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Detalles Bibliográficos
Autores principales: Ung, Matthew H., Wang, George L., Varn, Frederick S., Cheng, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356650/
https://www.ncbi.nlm.nih.gov/pubmed/27589846
http://dx.doi.org/10.18632/oncotarget.11776

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