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Generation of V α13/β21(+)T cell specific target CML cells by TCR gene transfer

Adoptive immunotherapy with antigen-specific T cells can be effective for treating melanoma and chronic myeloid leukemia (CML). However, to obtain sufficient antigen-specific T cells for treatment, the T cells have to be cultured for several weeks in vitro, but in vitro T cell expansion is difficult...

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Detalles Bibliográficos
Autores principales: Zha, Xianfeng, Xu, Ling, Chen, Shaohua, Yang, Lijian, Zhang, Yikai, Lu, Yuhong, Yu, Zhi, Li, Bo, Wu, Xiuli, Zheng, Wenjie, Li, Yangqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356659/
https://www.ncbi.nlm.nih.gov/pubmed/27713165
http://dx.doi.org/10.18632/oncotarget.12441