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The hedgehog inhibitor GANT61 sensitizes prostate cancer cells to ionizing radiation both in vitro and in vivo

Limited data exists regarding the combination of Hedgehog signaling (Hh) inhibition and radiotherapy, even though there are several indications that this might be a promising treatment strategy. In this study, we evaluated the combination of two Hh inhibitors, the SMO inhibitor GDC-0449 and the GLI...

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Detalles Bibliográficos
Autores principales:	Gonnissen, Annelies, Isebaert, Sofie, McKee, Chad M, Dok, Rüveyda, Haustermans, Karin, Muschel, Ruth J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356662/ https://www.ncbi.nlm.nih.gov/pubmed/27713179 http://dx.doi.org/10.18632/oncotarget.12483

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