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EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells

Cancer cells acquire essential characteristics for metastatic dissemination through the process of epithelial-to-mesenchymal transition (EMT), which is regulated by gene expression and chromatin remodeling changes. The enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the polycomb repress...

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Detalles Bibliográficos
Autores principales:	Cardenas, Horacio, Zhao, Janice, Vieth, Edyta, Nephew, Kenneth P., Matei, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356672/ https://www.ncbi.nlm.nih.gov/pubmed/27563817 http://dx.doi.org/10.18632/oncotarget.11497

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