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FGFR3, as a receptor tyrosine kinase, is associated with differentiated biological functions and improved survival of glioma patients
BACKGROUND: Activation of receptor tyrosine kinases is common in Malignancies. FGFR3 fusion with TACC3 has been reported to have transforming effects in primary glioblastoma and display oncogenic activity in vitro and in vivo. We set out to investigate the role of FGFR3 in glioma through transcripto...
Autores principales: | Wang, Zheng, Zhang, Chuanbao, Sun, Lihua, Liang, Jingshan, Liu, Xing, Li, Guanzhang, Yao, Kun, Zhang, Wei, Jiang, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356683/ https://www.ncbi.nlm.nih.gov/pubmed/27829236 http://dx.doi.org/10.18632/oncotarget.13139 |
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