Unraveling the expression of the oncogene YAP1, a Wnt/beta-catenin target, in adrenocortical tumors and its association with poor outcome in pediatric patients

BACKGROUND: Overexpression of the oncogene yes-associated-protein-1 (YAP1) is associated with increased cell proliferation in human cancers. YAP1 is a potential target of the Wnt/beta-catenin pathway, which plays an important role in adrenocortical tumors (ACT). The role of YAP1 in adrenocortical tu...

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Detalles Bibliográficos
Autores principales: Abduch, Rafael H., Bueno, Ana Carolina, Leal, Leticia F., Cavalcanti, Marcelo M., Gomes, Débora C., Brandalise, Silvia R., Masterallo, Maria J., Yunes, José A., Martinelli, Carlos E., Tone, Luiz G., Tucci, Silvio, Molina, Carlos A.F., Ramalho, Fernando S., Moreira, Ayrton C., Cardinalli, Izilda A., Scrideli, Carlos A., Ramalho, Leandra N.Z., de Castro, Margaret, Antonini, Sonir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356687/
https://www.ncbi.nlm.nih.gov/pubmed/27705928
http://dx.doi.org/10.18632/oncotarget.12382

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