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Alteration of colonic epithelial cell differentiation in mice deficient for glucosaminyl N-deacetylase/N-sulfotransferase 4

Glucosaminyl N-deacetylase/N-sulfotransferases (NDSTs) are the first enzymes that mediate the initiation of heparan sulfate sulfation. We previously identified NDST4 as a putative tumor suppressor in human colorectal cancer. In the study, we generated an Ndst4 knockout (Ndst4(−/−)) mouse strain and...

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Detalles Bibliográficos
Autores principales: Jao, Tzu-Ming, Li, Ya-Lin, Lin, Shu-Wha, Tzeng, Sheng-Tai, Yu, I-Shing, Yen, Sou-Jhy, Tsai, Ming-Hong, Yang, Ya-Chien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356710/
https://www.ncbi.nlm.nih.gov/pubmed/27793051
http://dx.doi.org/10.18632/oncotarget.12915

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