Thrombin inhibition and cisplatin block tumor progression in ovarian cancer by alleviating the immunosuppressive microenvironment

Cancer is often associated with an increased risk of thrombotic complications which can be aggravated by treatment with chemotherapeutics such as cisplatin. Multiple lines of evidence suggest that thrombin activity promotes tumor growth and metastasis. We examined the effect of co-treatment with dab...

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Detalles Bibliográficos
Autores principales: Alexander, Eric T., Minton, Allyson R., Peters, Molly C., van Ryn, Joanne, Gilmour, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356737/
https://www.ncbi.nlm.nih.gov/pubmed/27852034
http://dx.doi.org/10.18632/oncotarget.13300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356737/
https://www.ncbi.nlm.nih.gov/pubmed/27852034
http://dx.doi.org/10.18632/oncotarget.13300

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