Kallikrein-related peptidase 6 induces chemotherapeutic resistance by attenuating auranofin-induced cell death through activation of autophagy in gastric cancer

Kallikrein-related peptidase 6 (KLK6) is a biomarker of gastric cancer associated with poor prognosis. Mechanisms by which KLK6 could be exploited for chemotherapeutic use are unclear. We evaluated auranofin (AF), a compound with cytotoxic effects, in KLK6-deficient cells, and we investigated whethe...

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Detalles Bibliográficos
Autores principales: Kim, Tae Woo, Lee, Seon-Jin, Kim, Jong-Tae, Kim, Sun Jung, Min, Jeong-Ki, Bae, Kwang-Hee, Jung, Haiyoung, Kim, Bo-Yeon, Lim, Jong-Seok, Yang, Young, Yoon, Do-Young, Choe, Yong-Kyung, Lee, Hee Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356740/
https://www.ncbi.nlm.nih.gov/pubmed/27863404
http://dx.doi.org/10.18632/oncotarget.13352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356740/
https://www.ncbi.nlm.nih.gov/pubmed/27863404
http://dx.doi.org/10.18632/oncotarget.13352

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