Enumeration and targeted analysis of KRAS, BRAF and PIK3CA mutations in CTCs captured by a label-free platform: Comparison to ctDNA and tissue in metastatic colorectal cancer

Treatment of advanced colorectal cancer (CRC) requires multimodal therapeutic approaches and need for monitoring tumor plasticity. Liquid biopsy biomarkers, including CTCs and ctDNA, hold promise for evaluating treatment response in real-time and guiding therapeutic modifications. From 15 patients w...

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Detalles Bibliográficos
Autores principales: Kidess-Sigal, Evelyn, Liu, Haiyan E., Triboulet, Melanie M., Che, James, Ramani, Vishnu C., Visser, Brendan C., Poultsides, George A., Longacre, Teri A., Marziali, Andre, Vysotskaia, Valentina, Wiggin, Matthew, Heirich, Kyra, Hanft, Violet, Keilholz, Ulrich, Tinhofer, Ingeborg, Norton, Jeffrey A., Lee, Mark, Sollier-Christen, Elodie, Jeffrey, Stefanie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356741/
https://www.ncbi.nlm.nih.gov/pubmed/27863403
http://dx.doi.org/10.18632/oncotarget.13350

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