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Sorafenib pretreatment enhances radiotherapy through targeting MEK/ERK/NF-κB pathway in human hepatocellular carcinoma-bearing mouse model

Patients with unresectable hepatocellular carcinoma (HCC) usually have poor prognosis because current monotherapy including surgery, chemotherapy and radiotherapy (RT) are not effective. Combination therapy may be effective to overcome this clinical problem. Here, we proposed the combination of sora...

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Detalles Bibliográficos
Autores principales: Chen, John Chun-Hao, Chuang, Hui-Yen, Hsu, Fei-Ting, Chen, Yi-Chen, Chien, Yi-Chun, Hwang, Jeng-Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356748/
https://www.ncbi.nlm.nih.gov/pubmed/27863427
http://dx.doi.org/10.18632/oncotarget.13398