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Prevalence and clinical significance of BRCA1/2 germline and somatic mutations in Taiwanese patients with ovarian cancer
Germline and somatic BRCA1/2 mutations define a subset of patients with ovarian cancer who may benefit from treatment with poly (ADP-ribose) polymerase inhibitors. Unfortunately, data on the frequency of BRCA1/2 germline mutations in Taiwanese patients with ovarian cancer are scarce, with the preval...
Autores principales: | Chao, Angel, Chang, Ting-Chang, Lapke, Nina, Jung, Shih-Ming, Chi, Peter, Chen, Chien-Hung, Yang, Lan-Yan, Lin, Cheng-Tao, Huang, Huei-Jean, Chou, Hung-Hsueh, Liou, Jui-Der, Chen, Shu-Jen, Wang, Tzu-Hao, Lai, Chyong-Huey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5356755/ https://www.ncbi.nlm.nih.gov/pubmed/27907908 http://dx.doi.org/10.18632/oncotarget.13456 |
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